While deploying advanced artificial intelligence models for cybersecurity vulnerability discovery promises early defensive advantages, architecting defense solely around enterprise IT and cloud infrastructures leaves a massive blind spot across critical physical assets. An exploit in corporate IT typically leads to data exfiltration or temporary downtime, whereas an unmitigated vulnerability in operational technology can trigger open valves, catastrophic turbine failure, and direct threats to human life. This analysis examines why patching cycles in continuous 24/7 mission-critical operations span years rather than weeks, and why AI-assisted defense must place operational technology at the core of the table.